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Saturday, October 10, 2009

Human Genome Project

Must see,.......

The protein story...regarding structure

Proteins are Macromolecules composed of 20 different AMINO ACIDS(Essential amino acids) average structure or molecule of protein consisting of around 300 amino acids or 25oo atoms,the amino acids in proteins are covalently bonded and its the amino acid side chains deciding the chemical property of proteins including both structure and functions..usually proteins fold up into specific structures called as the secondary structures(alpha helix and beta sheets)...This video is all about how the proteins are in constant change...

What exactly is "BIOINFORMATICS"?

This is supposed to be the first question that shud pop up into every newbies brain but I think we can easily guess out the "literal" meaning as something that is involving BIO+INFORMATICS and can give you a simple answer by writing (BIO+INFORMATICS= BIOINFORMATICS).
In this blog i would like to depict the true works that goes on behind this simple equation...

What we study in bio informatics:
Biotechnology & its applications.
Micro & Molecular biology
Computing languages(C,C++,JAVA,.NET...).
Scripting languages (PERL, Python, Bio-PERL, Bio-RUBY..)
Database management system(DBMS), Relational(RDBMS)..
Sql, My-Sql.
Mathematical Concepts and applications involving integration, calculus, and graph theory..

In short Bioinformatics is the integrated application of all the above mentioned topics into further studies(Advanced study) involving:
GENOMICS
structural genomics
functional genomics
PROTEOMICS
NANOTECHNOLOGY
RECOMBINANT DNA TECHNOLOGY
ARTIFICIAL INTELLIGENCE (in biological mol. simulations)
GRID COMPUTING for datamanagement
SYSTEMS BIOLOGY
COMPUTATIONAL BIOLOGY
PHARMACOGENOMICS
PHARMACOGENETICS
BIOPHYSICS
BIOMEDICAL INFORMATICS
MATHEMATICAL BIOLOGY
PHARMACOINFORMATICS
AGROINFORMATICS
In-Silico ADME(Tox) prediction
CHEMINFORMATICS

Presentation of the Polymerase Chain Reaction(PCR)with audios,
hope is helpful for you all!!!!!
Nice presentation of DNA replication
This is how the DNA MicroArray technology actually works out...


Online tutorials on Protein Data location and retrieval.



SNPs

NCBI (National Center For Biotechnology Information)

The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health. The NCBI is located in Bethesda, Maryland(38.994994°N 77.099339°W ) and was founded in 1988 through legislation sponsored by Senator Claude Pepper. The NCBI houses genome sequencing data in GenBank and an index of biomedical research articles in PubMed Central and PubMed, as well as other information relevant to biotechnology. All these databases are available online through the Entrez search engine.

The NCBI is directed by David Lipman, one of the original authors of the BLAST sequence alignment program and a widely respected figure in Bioinformatics. He also leads an intramural research program, including groups led by Stephen Altschul (another BLAST co-author), David Landsman, and Eugene Koonin (a prolific author on comparative genomics).


Jobs

Application Specialist, 29th Sep 2009
Dreamers Consulting
Mumbai, 2-5 years, 4.30-6.70 lacs: The product range is called Process Monitoring tools, it is used to check the microbial contamination in microbiology labsThe product range comes under the umberalla of BIOPROCESS DIV